Heart valve

Technical capabilities in MPflow

• Multiphase CFD modelling of blood flow and cavitation in rotating machinery
• Advanced treatment of non-Newtonian fluid behaviour relevant to blood rheology
• High-resolution prediction of pressure fields and shear stresses
• Cavitation modelling including bubble inception, growth, and collapse dynamics
• Fully transient simulations for variable rotational speeds and pulsatile conditions
• Compatibility with complex geometries of VADs and heart valves

Our CFD approach

• High-fidelity simulation of centrifugal blood pumps and heart valve flows
• Resolution of unsteady flow structures and pressure fluctuations
• Accurate prediction of cavitation onset under low-pressure regions
• Coupled analysis of flow-induced stresses linked to hemolysis and thrombosis
• Transient modelling capturing real operating conditions and speed variations
• Detailed insight into flow separation, recirculation zones, and stagnation regions

Physics-based ML acceleration

• ML-enhanced prediction of pressure fields and cavitation regions
• Acceleration of transient simulations for rotating cardiovascular devices
• Hybrid CFD–ML framework ensuring physically consistent predictions
• Rapid estimation of hemolysis-relevant flow quantities (shear stress, exposure time)
• Real-time evaluation for design optimisation and digital twin integration

Why ML-CFD matters for Cardiovascular Devices

• Up to 1000× faster predictions: rapid evaluation of blood pump and valve designs
• 5–7× acceleration with ML-enhanced turbulence and multiphase modelling
• High accuracy (<5% deviation) in pressure fields and cavitation behaviour
• Instant assessment of transient conditions, including variable rotational speeds
• Supports medical safety by predicting hemolysis and thrombosis risk
• Reduces experimental testing and accelerates regulatory validation workflows